Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2005-05-10
2005-05-10
Duffy, Patricia A. (Department: 1645)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007900, C435S007920, C435S007950, C435S007100, C435S975000, C436S525000, C436S001000, C436S172000, C530S389100
Reexamination Certificate
active
06890727
ABSTRACT:
The disclosed invention relates to assays for detecting and quantifying Aβ peptide, using solid supports that are coated with heavy metal cations, such as zinc (II) or copper (II) form of a nitriloacetic acid. Further, diagnostic kits are described which are used to carry out the assays of the present invention. An improvement in an assay for detection of Aβ peptide is suggested which comprises forming a heavy metal cation/solid support complex. The preferred heavy metal cations for this improvement are zinc (II) or copper (II) form of a nitriloacetic acid. Finally, methods and kits for bulk purification of Aβ peptides from biological fluids are taught.
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Ma
Bush Ashley I.
Moir Robert D.
Tanzi Rudolph E.
Duffy Patricia A.
Sterne Kessler Goldstein & Fox P.L.L.C.
The General Hospital Corporation
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