Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1989-06-01
1993-08-10
Nucker, Christine M.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 792, 436516, 530350, 530395, G01N 33543, G01N 33561, C07K 1300, C07K 326
Patent
active
052348148
ABSTRACT:
A method to assist in the diagnosis of Alzheimer's disease comprising detecting, in bodily fluids, two APP-related proteins, in soluble form, said proteins have an apparent molecular size of about 130 kDa and about 35 kDa, and each of said proteins shares at least one epitope with the C-terminus of APP corresponding substantially to amino acids 676-695 of APP as shown in FIG. 1.
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Card John P.
Davis Leonard G.
Siman Robert G.
Christenbury Lynne M.
Du Pont Merck Pharmaceutical Company
Ferguson Blair Q.
Nucker Christine M.
Woodward M. P.
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