Diagnostic and prognostic methods for solid non-lymphoid tumors

Details Diagnostic and prognostic methods for solid non-lymphoid tumors Diagnostic and prognostic methods for solid non-lymphoid tumors

1993-09-09

1996-07-16

Scheiner, Toni R.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 79, 435 6, 436 64, 436813, G01N 3353, G01N 33574

Patent

active

055366422

ABSTRACT:
The present invention is directed to the measurement of cell-associated interleukin-2 receptor .alpha. (IL-2R.alpha.) expression in solid non-lymphoid tumors, and the use of such measurement In prognosing the metastatic potential of the tumor, diagnosing the metastatic localization of non-lymphoid tumor, and aiding the monitoring of efficacy of anticancer therapy against metastatic cells of non-lymphoid tumor. The present invention also relates to the use of T-cell receptor (tumor specific TCR.beta. idiotype) in monitoring the efficacy of anticancer therapy against non-lymphoid tumors.

REFERENCES:
patent: 4690915 (1987-09-01), Rosenberg
patent: 4789658 (1988-12-01), Yoshimoto et al.
patent: 4939093 (1990-07-01), McGrogan et al.
patent: 5006459 (1991-04-01), Kung et al.
patent: 5061488 (1991-10-01), Wiltrout et al.
patent: 5089261 (1992-02-01), Nitecki et al.
patent: 5089702 (1992-03-01), Zimmerman et al.
patent: 5126129 (1992-06-01), Wiltrout et al.
patent: 5229109 (1993-07-01), Grimm et al.
Barbera-Guillem et al., "Differences in the Lectin-binding patterns of the Periportal and Perivenous Endothelial Domains in the Liver Sinusoids" Journal of Hepatology, vol. 14, No. 1, 1991, pp. 131-139.
Barbera-Guillem et al., "Selective Implantation and Growth in Rats and Mice of Experimental Liver Metastasis in Acinar Zone One" Cancer Research, vol. 49, Jul. 15, 1989, pp. 4003-4010.
Yasumura, S., et al., Proc. Annu. Meet. Am. Assoc. Cancer Res., vol. 33: A 290, 1992.

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