Diagnostic agents and remedies for malignant tumors

Details Diagnostic agents and remedies for malignant tumors Diagnostic agents and remedies for malignant tumors

2005-06-14

2005-06-14

Helms, Larry R. (Department: 1642)

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Diagnostic or test agent produces in vivo fluorescence

C514S538000, C514S551000

Reexamination Certificate

active

06905671

ABSTRACT:
An agent for diagnosing or photokinetically treating malignant tumors, comprising as an active ingredient a compound in which at least one carbon atom of 5-aminolevulinic acid is a carbon isotope and/or a nitrogen atom in its amino group is a nitrogen isotope, or an ester, amide, salt, hydrate or solvate of the compound.

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Internal Search Report.
Gibson S L et al; “ Time-dependent intracellular accumulation of delta-aminolevulinic acid, induction of porphyrin synthesis and subsequent phototoxicity.” Photochemistry and Photobiology. Mar. 1997, vol. 65, No. 3, Mar. 1997, pp. 416-421, XP008030491.

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