Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1995-05-19
1998-11-03
Feisee, Lila
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
530350, 5303877, G01N 3350, G01N 3353, C07K 1630
Patent
active
058306765
ABSTRACT:
A new human gene termed MCC is disclosed. Antibody based methods and kits are provided for assessing mutations of the MCC gene in human tissues and body samples. Gross rearrangement and point mutations in MCC are observed in human tumor cells. MCC is expressed in most normal tissues. These results suggest that MCC is a tumor suppressor.
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Kinzler Kenneth W.
Nakamura Yusuke
Vogelstein Bert
White Raymond
Feisee Lila
Johnson Nancy A.
The Cancer Institute
The Johns Hopkins University
University of Utah
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