Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant...
Patent
1991-02-07
1992-03-10
Maples, John S.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
424 9, A61K 4902
Patent
active
050948350
ABSTRACT:
A method for the treatment and diagnosis of tumors is disclosed. This method comprises the direct administration of an effective anti-tumor amount of a radiohalogenated pyrimidine nucleoside such as .sup.123 IUdR to the affected site.
REFERENCES:
Mercer, J. R. et al., "Synthesis and Tumor Uptake of . . . Uracils", J. Med. Chem., 32, 1989, pp. 1289-1294.
Robins et al., "Iodine-123-Iododeoxyuridine: . . . ", J. Nucl. Med. Biol., vol. 8, 1981, pp. 53-63.
Adelstein S. James
Kassis Amin I.
Maples John S.
The President and Fellows of Harvard College
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