Diagnosis of Shigella dysenteriae

Details Diagnosis of Shigella dysenteriae Diagnosis of Shigella dysenteriae

1984-07-13

1988-02-09

Warden, Robert J.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving viable micro-organism

435 4, 435 34, 435803, 436501, 536 11, 536 53, 536123, C12Q 110

Patent

active

047242051

ABSTRACT:
A composition for therapeutic or diagnostic use in connection with the toxine of Shigella dysenteriae. As an active constituent the composition contains or consists of a compound having the formula (I): ##STR1## wherein R.sub.1 is hydrogen or an organic residue, and R.sub.2 is hydrogen, alkyl, alkoxi or a carbohydric residue with the proviso that R.sub.2 is not .beta.-D-GalNacp-(1-0) when R.sub.1 is D-Glc or -.beta.-D-Glcp-(1-0)-ceramide and that R.sub.2 is different from OH,

REFERENCES:
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Chemical Abstracts 77: 29859n.
Chemical Abstracts 90: 121907t.
Chemical Abstracts 93: 198591e.
Microbiology Including Immunology and Molecular Genetics, Davis, B. D. et al. (eds), third edition, Harper and Row Publishers, 1980, pp. 646-665.
Brown, J. E. et al., "Inhibition of Protein Synthesis in Intact HeLa Cells by Shigella dysenteriae 1 Toxin", Infection and Immunity, Jul., 1980, pp. 98-107.
Brown, J. E. et al., "Purification and Biological Characterization of Shiga Toxin from Shigella dysenteriae 1", Infection and Immunity, Jun., 1982, pp. 99-1005.
Olsnes, S. et al., "Isolation and Characterization of Shigella shigae Cytotoxin", The Journal of Biological Chemistry, vol. 255, No. 1, Jan., 1980, pp. 284-289.

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