Diagnosis of predisposition to osteoporosis

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 912, 435810, 536 235, 536 2431, 536 2433, 935 8, 935 78, C12Q 168, C07H 2104, C12P 1934

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059225424

ABSTRACT:
Diagnostic means that determines the genotype of a collagen gene of an individual is described. A polymorphism in the collagen gene correlates with predisposition to osteoporosis, so diagnosis of a predisposition is achieved using the diagnostic means. An isolated gene comprising the nucleotide substitution of the polymorphism is also described, as is a method of diagnosis based on the presence or absence of the polymorphism.

REFERENCES:
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