Diagnosis of parasites

Details Diagnosis of parasites Diagnosis of parasites

2007-12-04

2007-12-04

Navarro, Mark (Department: 1645)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

Reexamination Certificate

active

11270287

ABSTRACT:
Detection ofPlasmodiumssp. by analysis of extrachromosomal DNA. It has been found that the molecular composition, physical arrangements, and nucleotide sequences of the extrachromosomal plastid-like element and mitochondrial element are highly conserved in differentPlasmodiumssp. The high degree of homology has been used to design genera-specific or species specific diagnostic assays with a low frequency of false negatives. Plastid and mitochondrial DNA sequences are disclosed. The use of the sequences is claimed for detection, prophylactic, and therapeutic treatment ofPlasmodiumssp. infection in human or other animals.

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