Diagnosis of neurodegenerative disease

Details Diagnosis of neurodegenerative disease Diagnosis of neurodegenerative disease

1996-10-02

1999-09-28

Myers, Carla J.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 71, 435 912, 536 231, 536 235, 536 243, 536 2433, 530350, 5303871, C12Q 168, C07H 2104, G01N 3353

Patent

active

059586842

ABSTRACT:
The invention encompasses methods and reagents for the diagnosis of a disease caused by or associated with a gene having a somatic mutation giving rise to a frameshift mutation. The methods include the steps of providing a body fluid or tissue sample from a patient; and analyzing the sample for the presence of a gene having a frameshift mutation or a protein encoded thereby, wherein the presence of the mutated gene or encoded protein is indicative of the disease.

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