Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1995-03-09
1996-12-24
Stanton, Brian R.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 4, 435 71, 435 794, 435 18, 435 30, 435 34, 435201, 435960, 436800, 436801, 436804, 436805, G01N 3353, G01N 33532, G01N 33536, G01N 33569
Patent
active
055872921
ABSTRACT:
A novel method for detecting chitin, and for diagnosing fungal infections (including yeast infections), with a chitinase or other chitin-specific binding protein. This method should allow the convenient, broad spectrum diagnosis of fungal infections in tissue samples or in body fluids. Fungal infections are a particular problem in immunocompromised hosts such as AIDS patients, where they can cause opportunistic infections. This invention overcomes difficulties experienced by prior methods of diagnosing fungal infections.
REFERENCES:
patent: 3862007 (1975-01-01), Smirnoff et al.
patent: 5004699 (1991-04-01), Winters et al.
patent: 5352607 (1994-10-01), Laine et al.
ATCC (1985) In Catalog of Bacteria, Phages and rRNA vectors p. 213.
Davis et al. (1980) in Microbiology, 3rd Ed. Harper, Row, N.Y. pp. 818-820.
Voller et al. (1976.) in Manual of Clinical Immunology.
Rose et al., Eds. American Soc. Microbiol. pp. 506-512.
Collaborative Research Inc. Catalog (1989) p. 28.
Ohtakara et al. 1979. J. Ferment. Technology 57(3):169-177. Abstract Only.
Chamberland, et al, "Chitinase-Gold Complex Used to Localized Chitin Ultrastructurally in Tomato Root Cells," Histochem. J., vol. 17, pp. 313-321.
Ou, et al, "Isolation, Characterization and Molecular Cloning of an Endo-Chitinase from Vibrio parahemolyticus," Louisiana State University draft manuscript (1991).
Lo, et al, "DNA Sequence and High Expression Level for an Endo-Chitinase from Vibrio parahemolyticus," Louisana State University draft manuscript (1991)..
Benhamou, et al, "Attempted Localization of a Substrate for Chitinases in Plant Cells Reveals Abundant N-acetyl-D-glucosamine Residues in Secondary Walls," Biology of the Cell, vol. 67, No. 3, pp. 341-350 (1989).
M. A. Benjaminson, "Conjugates of Chitinase with Fluorescein Isothiocyanate or Lissamine Rhodamine as Specific Stains for Chitin In Situ," Stain Technology, vol. 44, pp. 27-31 (1969).
M. A. Benjaminson et al.,"Ferritin-Labelled Enzyme: a Tool or Electron Microscopy," Nature, vol. 210, pp. 1275-1276 (1966).
R. P. Haugland, "Molecular Probes Handbook of Fluorescent Probes and Research Chemicals" (1992).
M. Meyberg, "Selective Staining of Fungal Hyphae in Parasitic and Symbiotic Plant-Fungus Associations," Histochemistry, vol. 88, pp. 197-199 (1988).
G. Marquis et al., "Histochemical and Immunochemical Study of the Fate of Candida albicans inside Human Neutrophil Phagolysosomes," J. Leukocyte Biol., vol. 50, pp. 587-599 (1991).
M. E. Young, et al., "Kinetics of Chitinase Production. I. Chitin Hydrolysis," Biotech. and Bioeng., vol. 27, pp. 769-775 (1985).
C. Jeuniaux, "Recherches Sur Les Chitinases, II.-Purification de la Chitinase d'un Streptomycete, et Separation Electrophoretique de Principes Chitinolytiques Distincts," Arch. Int. Physiol. Biochem., vol. 67, pp. 597-617 (1959).
Y. Tominaga et al., "Purification and Some Properties of Two Chitinases from Streptomyces orientalis which Lyse Rhizopus Cell Wall," Agr. Biol. Chem., vol. 40, pp. 2325-2333 (1976).
A. Ohtakara et al., "Purification and Some Properties of Chitinase from Vibrio sp.," J. Ferment. Technol., vol. 57, pp. 169-177 (1979).
J. Molano et al., "A Rapid and Sensitive Assay for Chitinase Using Tritiated Chitin," Anal. Biochem., vol. 83, pp. 648-656 (1977).
R. A. Tom et al., "Effect of Reaction Conditions on Hydrolysis of Chitin by Serratia marcescens QMB1466 Chitinase," J. Food Sci., vol. 46, pp. 646-647 (1981).
A. T. Bull, "Inhibition of Polysaccharases by Melanin: Enzyme Inhibition in Relation to Mycolysis ," Arch. Biochem. Biophys., vol. 137, pp. 345-356 (1970).
M. Charpentier et al., "The Chitin-Degrading Enzyme System of a Streptomyces Species," Int. J. Biochem. vol. 15, pp. 289-292 (1983).
A. Otakara, "Studies on the Chitinolytic Enzymes of Black-koji Mold. Part II. Purification of Chitinase," Agr. Biol. Chem., vol. 25, pp. 54-60 (1961).
E. Danulat, "Role of bacteria with regard to chitin degradation in the digestive tract of the cod Gadus morhua," Mar. Biol., vol. 90, pp. 335-343 (1986).
Laine Roger A.
Lo Wai C. J.
Board of Supervisors of Louisiana State University and Agricultu
Runnels John H.
Stanton Brian R.
LandOfFree
Diagnosis of fungal infections with a chitinase does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Diagnosis of fungal infections with a chitinase, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Diagnosis of fungal infections with a chitinase will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1178063