Diagnosis of free fatty acid toxicity by monitoring red blood ce

Details Diagnosis of free fatty acid toxicity by monitoring red blood ce Diagnosis of free fatty acid toxicity by monitoring red blood ce

1987-09-23

1989-10-10

Sneed, H. M. S.

Optics: measuring and testing

Blood analysis

436811, G01N 3348

Patent

active

048727520

ABSTRACT:
The present invention consists of a method for diagnosing free fatty acid toxicity, particularly resulting from parenteral fat emulsion. Specifically, red cell morphology is microscopically monitored to detect specific abnormal alterations resulting from various degrees of free fatty acid toxicity.

REFERENCES:
Siegel et al., "Defense Against Infection-A Selective Role for Unsatured Fatty Acid" (Symposium Abstracts) Am. J. Reprod. Immunol. 3(4):197 (1983).
Greisman, "Hyperlipemia and Hemolysis I. Interaction of Sodium Oleate with Human Erythrocytes" Proc. Soc. Exp. Biol. Med. 101:117-122 (1954) (see first paragraph, p. 177).
Ross et al., "Acquired Stomatocytosis in Infants Receiving Parenteral Fat Emulsion" Pediatr. Res. 12 (4II) 473 (1978).
Siegel et al., "Parenteral Fat Emulsions and Immune Adherence" JAMA251(12)1574-1579 (03/23/84).

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