Surgery – Truss – Pad
Patent
1995-06-06
1997-04-29
Smith, Ruth S.
Surgery
Truss
Pad
A61B 600
Patent
active
056239327
ABSTRACT:
Apparatus and in vivo methods to distinguish normal and abnormal cervical tissue and to detect cervical intraepithelial neoplasia (CIN) in a diagnostic cervical tissue sample. Induced fluorescence intensity spectra from known normal cervical tissue and a diagnostic tissue sample are obtained from the same patient. Peak fluorescence intensity values for normal tissue samples are averaged, as are slope measurements from predetermined portions of spectra induced in both known normal cervical tissue and the diagnostic tissue sample. Peak fluorescence intensities of diagnostic tissue spectra are divided by average peak fluorescence intensity values for normal tissue in the same patient to yield relative peak fluorescence intensity values. Normal and abnormal cervical tissues are distinguished using a predetermined empirical discriminant function of slope measurements derived from normal tissue spectra and relative peak fluorescence intensity measurements in the same patient. CIN is distinguished from tissue with human papilloma virus infection or inflammation using a predetermined empirical discriminant function of average slope measurements on spectra from known normal tissue and slope measurements on a diagnostic tissue spectrum.
REFERENCES:
patent: 5348018 (1994-09-01), Alfano et al.
patent: 5408996 (1995-04-01), Salb
patent: 5421339 (1995-06-01), Ramanujam et al.
Mahadevan Anita
Mitchell Michele F.
Ramanujam Nirmala
Richards-Kortum Rebecca R.
Thomsen Sharon
Board of Regents , The University of Texas System
Smith Ruth S.
LandOfFree
Diagnosis of dysplasia using laser induced fluorescence does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Diagnosis of dysplasia using laser induced fluorescence, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Diagnosis of dysplasia using laser induced fluorescence will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-699693