Diagnosis and treatment of fluke infections with monoclonal anti

Details Diagnosis and treatment of fluke infections with monoclonal anti Diagnosis and treatment of fluke infections with monoclonal anti

1981-08-28

1983-11-22

Padgett, Benjamin R.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

436548, 436536, 424 9, G01N 3300

Patent

active

044168667

ABSTRACT:
Antibodies and antigens are disclosed which provide a method of detecting and a method of combating flukes. Fluke infections are screened by determining presence of fluke antigens defined by antibodies produced by hybridomas ATCC HB-8086 and HB-8087. Chronic and acute fluke infections are distinguished by determining presence of fluke spine protein. Fluke infections are combated by injecting warm-blooded animals with antibodies produced by hybridomas ATCC HB-8086, HB-8087 and HB-8088, or with proteins defined by those antibodies.

REFERENCES:
Biological Abstracts, vol. 70(II), p. 7495, Abstract 71676, Verwaerde et al., (1980).
Proc. National Acad. Sci. USA, vol. 78(5), pp. 3165-3169, (1981), Mitchell et al.
Aust. J. Exp. Biol. Med. Sci., vol. 57, pp. 287-302 (1979), Mitchell et al.
C. R. Acad. Sc. Paris, t. 289 (Oct. 29, 1979), Serie D--725 (Translation Provided).

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