Diagnosis and treatment of disorders of iron metabolism

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C436S066000, C436S068000

Reexamination Certificate

active

07659074

ABSTRACT:
The invention concerns a method for detecting disorders of iron metabolism and in particular the differential diagnosis of disorders of iron metabolism by means of three independent parameters. The differential diagnosis can be used to classify disorders of iron metabolism and to recommend the required treatment and to monitor the progress and response to treatment.

REFERENCES:
Feelders et al. Regulation of iron metabolism in the acute phase response:IFNg and TNFa induce hypoferraemia, ferritin production and a decrease in circulating transferrin receptors in can European Journal of Clinical Investigation vol. 28, 520-527 (1998).
Suominen et al. Single values of serum transferrin receptor and transferrin receptor ferritin index can be used to detect true and functional iron deficiency in rheumatoid arthritis . . . Arthritis & Rheumatism, vol. 43, No. 5 pp. 1016-1020 (May 2000).
Lehmann, et al. S-transferrin-receptor, ferritin and CRP as markers in differential diagnosis of anemias of chronic inflammatory processes. (Abstract, Clinical Chemistry and Laboratory Medicine, vol. 47, No. 6 Supplement, Jul. 2001).
Looker et al., Increased serum transferrin saturatation is associated with lower serum transferrin receptor concentration. Clinical Chemistry 45:12 pp. 2191-2199 (1999).
Fishbane et al., Reticulocyte hemoglobin content in the evaluation of iron status of hemodialysis patients. Kidney International 52:217-222 (1997).
Bovy, et al.,Factors determining the percentage of hypochromic red blood cells in hemodialysis patients, Kidney International, vol. 56, pp. 1113-1119 (1999).
Tessitore, et al.,The role of iron status markers in predicting response to intravenous iron in haemodialysis patients on maintenance erythropoietin, Nephrology Dialysis Transplantion, vol. 16, pp. 1416-1423 (2001).
Thomas, et al.,Biochemical Markers and Hematologic Indices in the Diagnosis of Functional Iron Deficiency, Clinical Chemistry, vol. 48, pp. 1066-1076 (2002).
Hasegawa, Midori, et al., Evaluation of reticulocyte hemoglobin content, percentage of hypochromic red blood cells, and ratio of serum transferring receptor level/serum iron level as markers of iron-deficiency erythropoiesis in patients undergoing hemodialysis, NLM Database accession No. NLM12216478 XP002247472 abstract of Nippon Jinzo Gakkai Shi, Japan 2002, vol. 44, No. 5, pp. 453-463, ISSN: 0385-2385.
Little, David R.,Hemochromatosis: Diagnosis and Management, American Family Physician, 53:2623-2628 (1996).
Remacha, A., et al.,The role of serum transferring receptor in the diagnosis of iron deficiency, Haematologica, 83:963-966 (1998).
Beguin, Y., et al.,Acute functional iron deficiency in obese subjects during a very-low energy all-protein diet, American Journal of Clinical Nutrition, 66:75-79 (1997).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Diagnosis and treatment of disorders of iron metabolism does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Diagnosis and treatment of disorders of iron metabolism, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Diagnosis and treatment of disorders of iron metabolism will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4217634

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.