Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2007-02-27
2007-02-27
Helms, Larry R (Department: 1643)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S004000, C436S063000, C436S064000
Reexamination Certificate
active
10185369
ABSTRACT:
The invention is based on the elucidation of a mechanism by which HPV promotes oncogenesis and provides a methods of diagnosing malignant tumors and methods of preventing the development of malignancies or inhibiting tumor growth. A method for diagnosing a neoplasm in a mammal is carried out by measuring the level of helicase-like transcription factor (HLTF) in tissue of the mammal. An increase in the level of HLTF in the tissue compared to the level in a normal control tissue indicates the presence of a neoplasm in the tissue.
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Androphy Elliot J.
Belayew Alexandra
Doshi Nishita
Beattie Ingrid A.
Helms Larry R
Holleran Anne L.
Mintz Levin Cohn Ferris Glovsky and Popeo P.C.
New England Medical Center
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