Diagnosis and prognosis of breast cancer patients

Details Diagnosis and prognosis of breast cancer patients Diagnosis and prognosis of breast cancer patients

2011-01-04

2011-01-04

Moran, Marjorie (Department: 1631)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C702S019000, C536S023100

Reexamination Certificate

active

07863001

ABSTRACT:
The present invention relates to genetic markers whose expression is correlated with breast cancer. Specifically, the invention provides sets of markers whose expression patterns can be used to differentiate clinical conditions associated with breast cancer, such as the presence or absence of the estrogen receptor ESR1, and BRCA1 and sporadic tumors, and to provide information on the likelihood of tumor distant metastases within five years of initial diagnosis. The invention relates to methods of using these markers to distinguish these conditions. The invention also relates to kits containing ready-to-use microarrays and computer software for data analysis using the statistical methods disclosed herein.

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