Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1993-08-09
1995-10-31
Scheiner, Toni R.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 72, 435 23, 435 24, 436501, 436 63, G01N 33543, G01N 33544, G01N 3368
Patent
active
054628571
ABSTRACT:
The present invention relates to a method of diagnosing malignant hyperthermia susceptibility by detecting abnormal ryanodine receptor fragments following proteolytic enzyme digestion of ryanodine receptors isolated from the sarcoplasmic reticulum of mammalian skeletal muscle. The detection of abnormal ryanodine receptor fragments is indicative of malignant hyperthermia susceptibility.
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Campbell Kevin P.
Kahl Steven D.
Knudson C. Michael
Louis Charles F.
Mickelson James R.
Farrell Kevin M.
Parsons Nancy J.
Scheiner Toni R.
University of Iowa Research Foundation
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