Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1990-08-06
1993-09-07
Nucker, Christine M.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 24, 436530, 436 63, 5303871, C12Q 100, C12Q 137, G01N 3353, G01N 33544
Patent
active
052428010
ABSTRACT:
The present invention relates to a method of diagnosing malignant hyperthermia susceptibility by detecting abnormal ryanodine receptor fragments following proteolytic enzyme digestion of ryanodine receptors isolated from the sarcoplasmic reticulum of mammalian skeletal muscle. The detection of abnormal ryanodine receptor fragments is indicative of malignant hyperthermia susceptibility.
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Campbell Kevin P.
Kahl Steven D.
Knudson C. Michael
Louis Charles F.
Mickelson James R.
Nucker Christine M.
Preston D. R.
Regents of the University of Minnesota
University of Iowa Research Foundation
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