Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1977-05-03
1978-08-08
Thomas, Jr., James O.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
560109, A61K 3124, C07C 6976
Patent
active
041057872
ABSTRACT:
This invention covers diacylated derivatives of .gamma.-glutamyl dopamine selected from the group consisting of ##STR1## where R is a C.sub.1 -C.sub.12 straight or branched chain alkyl radical, a phenyl ring or a substituted phenyl ring and R' is H or a C.sub.1 -C.sub.7 alkyl, and a pharmaceutically acceptable acid addition salt thereof.
The compounds of this invention are useful to increase the renal blood flow by being administered to warm-blooded animals by clinically accepted routes of administration such as oral, parenteral, rectal and the like.
REFERENCES:
patent: 3676492 (1972-07-01), Biel et al.
patent: 3891696 (1975-06-01), Bodor et al.
patent: 3903147 (1975-09-01), Kyncl et al.
patent: 3907864 (1975-09-01), Biel et al.
patent: 3910988 (1975-10-01), Jones et al.
patent: 4017636 (1977-04-01), Jones et al.
Curs Carroll W.
Jones Peter H.
Kyncl Jaroslav
Abbott Laboratories
Breitenstein G. T.
Burgauer Paul D.
Niblack Robert L.
Thomas, Jr. James O.
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