Diabetic control by combined insulin forms

Details Diabetic control by combined insulin forms Diabetic control by combined insulin forms

1988-01-13

1989-09-05

Schain, Howard E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 3, C07K 740

Patent

active

048638960

ABSTRACT:
Peripherally administered insulin fails to provide liver hormone function. Hepatocyte directed vesicles with encapsulated insulin will restore liver function, but there is no non-targeted insulin to bypass the liver for peripheral use, as in natural, healthy body function.
Whenever a prescribed dosage of insulin is divided between free and encapsulated hepatocyte targeted forms, a very small fraction of the dose in encapsulated form is sufficient to elicit full liver function, and non-targeted insulin supplies the needs of the body muscle and tissue.

REFERENCES:
patent: 4377567 (1983-03-01), Geho
patent: 4603044 (1986-07-01), Geho et al.

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