Di-substituted 1,2-dioxetane compounds having increased water so

Details Di-substituted 1,2-dioxetane compounds having increased water so Di-substituted 1,2-dioxetane compounds having increased water so

1997-04-16

1998-09-08

Owens, Amelia

Compositions

Chemiluminescent

435 4, C09K 300

Patent

active

058041036

ABSTRACT:
Stable, enzymatically triggered chemiluminescent 1,2-dioxetanes with improved water solubility are provided. Dioxetanes further substituted with two or more water-solubilizing groups disposed on the dioxetane structure provide superior performance by eliminating the problem of reagent carryover when used in assays performed on capsule chemistry analytical systems. Compositions comprising a dioxetane with two or more water-solubilizing groups, a non-polymeric cationic surfactant enhancer and optionally a fluorescer, for providing enhanced chemiluminescence are also provided.

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