Di-substituted 1,2-dioxetane compounds having increased water so

Details Di-substituted 1,2-dioxetane compounds having increased water so Di-substituted 1,2-dioxetane compounds having increased water so

1995-07-31

1998-07-07

Owens, Amelia

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

536 71, 560 60, 558180, C07D32100, C07C 6976, C07F 902

Patent

active

057771359

ABSTRACT:
Stable, enzymatically triggered chemiluminescent 1,2-dioxetanes with improved water solubility are provided. Dioxetanes further instituted with two or more water-solubilizing groups disposed on the dioxetane structure provide superior performance by eliminating the problem of reagent carryover when used in assays performed on capsule chemistry analytical systems. Compositions comprising a dioxetane with two or more water-solubilizing groups, a non-polymeric cationic surfactant enhancer and optionally a fluorescer, for providing enhanced chemiluminescence are also provided.

REFERENCES:
patent: 4952707 (1990-08-01), Edwards
patent: 4959182 (1990-09-01), Schaap
patent: 5004565 (1991-04-01), Schaap
patent: 5013827 (1991-05-01), Schaap
patent: 5068339 (1991-11-01), Schaap
patent: 5112960 (1992-05-01), Bronstein
patent: 5145772 (1992-09-01), Voyta
patent: 5220005 (1993-06-01), Bronstein
patent: 5393469 (1995-02-01), Akhavan-Tafti
patent: 5399497 (1995-03-01), Kumar
Schaap, A.P., et al., Tetrahedron Lett., 28(9), 935-8 (1987).
Schaap, A.P., et al., Tetrahedron Lett., 28(11), 1159-62 (1987).
Schaap, A.P., Photochem. Photobiol., 47S, 50S (1988).
Schaap, A.P., Clinical Chemistry, 35(9), 1863-4 (1989).
Martin Josso, Ph.D. Thesis, Wayne State Univ. (1992), Diss. Abs. Int., vol. 53, No. 12B, p. 6305.

Affiliated with

Also associated with

Rating

Di-substituted 1,2-dioxetane compounds having increased water so does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Di-substituted 1,2-dioxetane compounds having increased water so, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Di-substituted 1,2-dioxetane compounds having increased water so will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1207508