Di-enzymatic dentifrice

Details Di-enzymatic dentifrice Di-enzymatic dentifrice

1981-08-13

1986-03-25

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Dentifrices

Ferment containing

424 94, A61K 728, A61K 3748

Patent

active

045782652

ABSTRACT:
A di-enzymatic dentifrice is provided which contains an oxidizable substrate and an oxidoreductase enzyme specific to such substrate for producing hydrogen peroxide upon oral application of the dentifrice and further contains a thiocyanate salt and lactoperoxidase for interacting with hydrogen peroxide to produce a hypothiocyanate bacterial inhibitor. An illustrative enzymatic system for this purpose contains glucose, glucose oxidase, potassium thiocyanate and lactoperoxidase.

REFERENCES:
patent: 1169998 (1916-02-01), Rhodes
patent: 1739586 (1929-12-01), Gerngross et al.
patent: 1740543 (1929-12-01), Gerngross et al.
patent: 4012839 (1977-03-01), Hill
patent: 4150113 (1979-04-01), Hoogendoorn et al.
patent: 4178362 (1979-12-01), Hoogendoorn et al.
patent: 4269822 (1981-05-01), Pellico et al.
patent: 4320116 (1982-03-01), Bjorck

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