Di(aromatic) compounds and their use in human and veterinary med

Details Di(aromatic) compounds and their use in human and veterinary med Di(aromatic) compounds and their use in human and veterinary med

1993-12-16

1995-08-08

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514354, 514448, 514461, 514467, 514513, 514532, 514544, 514568, 514569, 514599, 514617, 546313, 546314, 546315, 546316, 546318, 546321, 546322, 546326, 548527, 548517, 548539, 549 71, 549 77, 549483, 549484, 549485, 549486, 549487, 549488, 558230, 558257, 560 8, 560 73, 560100, 560106, 562442, 564 74, 564180, 564184, A61K 31165, A61K 3119, A61K 31235, C07C 6976

Patent

active

054399254

ABSTRACT:
Di(aromatic) compounds corresponding to the following formula: ##STR1## in which: Ar represents either ##STR2## n=1 or 2 or: ##STR3## X represents a divalent radical, Z represents O, S or a divalent radical, and R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 represent a hydrogen atom or various organic radicals, and the salts of the compounds of formula (I) when R.sub.1 is a carboxylic acid function. Use is in human and veterinary medicine and in cosmetics.

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Kagechika, "Retinobenzoic Acid, 4. Conformation of Aromatic Amides with Retinoidal Activity, Importance of Trans-Amide Structure for the Activity", Chemical Abstracts, vol. 111, No. 15, 1989, Abstract No. 134547c.

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