Di and tri-O-acetyl-"O-iso-valeryl-23-O-demycinosyl tylosins, hy

Details Di and tri-O-acetyl-"O-iso-valeryl-23-O-demycinosyl tylosins, hy Di and tri-O-acetyl-"O-iso-valeryl-23-O-demycinosyl tylosins, hy

1985-12-23

1989-07-25

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536124, C07H 1708

Patent

active

048515183

ABSTRACT:
There are disclosed novel di- and tri-O-acetyl-23-O-demycinosyl-4"-O-iso-valeryltylosins and the pharmaceutically acceptable salts thereof, which have improved activity as antibacterials and provide higher blood levels than other tylosin derived compounds. These compounds have the following structural formula ##STR1## wherein R is acetyl or hydrogen and z is for example O or ##STR2##

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