DHEA Formulations and methods for treating dry skin

Details DHEA Formulations and methods for treating dry skin DHEA Formulations and methods for treating dry skin

1985-01-24

1985-09-17

Roberts, Elbert L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

A61K 3156

Patent

active

045421293

ABSTRACT:
Topical formulations for treating dry skin with dehydroepiandrosterone (DHEA) may contain a keratolytic agent to counteract the formation of acne-like skin lesions without diminishing the effectiveness of DHEA in increasing sebum production. The keratolytic agent may be a hydroxybenzoic acid, alpha-hydroxycarboxylic acid or urea, with salicylic acid being preferred. The DHEA and keratolytic agent may be formulated in a non-toxic, dermatologically acceptable vehicle including tinctures, creams, ointments, gels and lotions.

REFERENCES:
patent: 3162631 (1964-12-01), Pike
Chemical Abstracts (1969) vol. 70, Par. 34,7768, an abstract of a publication by Pochi et al., "J. Invest. Dermatol.", 1969, 52(1) 32-36.
Chemical Abstracts (1970) vol. 72, par. 118,214n, an abstract of a publication by Oertel et al., "Hoppe-Sayler's Z. Physiol. Chem.", 1970 351(3) pp. 84-86 (Germ.).

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