Dextrin sulfates and anti HIV-1 agents and composition thereof

Details Dextrin sulfates and anti HIV-1 agents and composition thereof Dextrin sulfates and anti HIV-1 agents and composition thereof

1995-03-24

2000-01-18

Peselev, Elli

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 54, 514 60, 514885, 536103, A61K 3170

Patent

active

060157992

ABSTRACT:
This invention provides an agent against HIV-1 and related viruses, the agent being or including dextrin sulphate containing at most two sulphate groups per glucose unit. The invention also provides a composition containing such an agent, and the use of the agent or composition against HIV-1 and related viruses. By restricting the degree of substitution of the dextrin sulphate to a maximum of 2, the invention makes it possible to produce a dextrin sulphate having adequate anti-HIV activity whilst maintaining toxicity within acceptable limits.

REFERENCES:
patent: 2967178 (1961-01-01), Kerr et al.
patent: 4840941 (1989-06-01), Ueno et al.
patent: 5153181 (1992-10-01), Diringer et al.
patent: 5221669 (1993-06-01), Anand et al.
patent: 5258175 (1993-11-01), Davies

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