Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1993-06-21
1996-04-16
Seidleck, James J.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
424426, 4283144, 4283155, 4283186, 4283197, 4283188, 604358, 604369, 604370, 604371, 606 1, 128899, 521 51, 521 61, 521916, B32B 326
Patent
active
055080367
ABSTRACT:
A device for preventing adhesions or binding of tissue to tissue or of tissue to bone which comprises a composite of a first layer and a second layer, each of which comprises a biodegradable polymer. The first layer is selected from the group consisting of a non-porous layer and a porous layer having a pore size no greater than 3.mu.. The second layer has pores which have a pore size of from about 30.mu. to about 250.mu.. Such a composite device provides for tissue growth into the second layer, while the first layer acts as an adhesion-preventing barrier, and enables attachment of the device to tissue without suturing. Alternatively, the device comprises the first layer hereinabove mentioned and a second layer which is an adherence layer and which adheres to tissue and/or bone.
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patent: 5185408 (1993-02-01), Tang et al.
Lawson, et al., SPINE, vol. 16, No. 6 Supplement, pp. S222-S226 (1991) Jun.
A. M. Reed and D. K. Gilding; Biodegradable polymers for use in Surgery; Polymer; 1981; Apr.; vol. 22; pp. 499-504.
D. K. Gilding and A. M. Reed; Biodegradable Polymers for Use in Surgery; Polymer; Dec., 1979; vol. 20; pp. 1454-1458.
Bakker Dirkjan
Bakkum Erica A.
van Blitterswijk Clemens A.
Johnson R. F.
Lillie Raymond J.
Olstein Elliot M.
Osteotech Inc.
Seidleck James J.
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