Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals
Patent
1989-06-20
1990-12-25
Hill, Jr., Robert J.
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
422 57, 422 58, 422 61, 422 69, 422102, 436510, 436807, 436810, 436 81B, G01N 33543, G01N 3376
Patent
active
049802984
ABSTRACT:
A device for carrying out chemical or clinical testing of a liquid sample, for example a urine sample, by a specific binding assay, said device comprising a test compoenent (2) which has a sensitised solid surface (2a) carrying an immobilized component of a specific binding pair relevant to the essay, and a handling piece (1), and characterized in that the test component (2) bearing the sensitized surface (2a) is removably mounted in spaced relationship with a removably mounted accessory component (4) carrying an accessory solid surface (5), and in that there is a space (4a) between the sensitized surface (2a) and the removable accessory component (4) to act as a container for sample liquid, so that when the device is contacted with a sample liquid source or immersed in liquid which is to provide the test sample, liquid of the sample can enter the space (4a) to contact the sensitized surface (2a), and the accessory surface (5) acts to retain and contain sample liquid in contact with the sensitized surface (2a) even after removal of the device from further contact with or immersion in the source of sample liquid, and in that the test component (2) is so formed that after removal of the removable accessory component (4) the sensitized surface (2a) is left exposed and accessible to further treatment liquid such as washing liquid and/or reagents.
REFERENCES:
patent: 4200613 (1980-04-01), Alfrey
patent: 4305924 (1981-12-01), Piasio
patent: 4425320 (1984-01-01), Perry et al.
patent: 4482521 (1984-11-01), Bunce
patent: 4495151 (1985-01-01), Ohyama
patent: 4742011 (1988-05-01), Blake
Blake Anthony
Coley John
Smith Ronald
Hill Jr. Robert J.
Unilever Patent Holdings B.V.
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