Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus
Reexamination Certificate
2007-05-08
2007-05-08
Whiteman, Brian (Department: 1635)
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Genetically modified micro-organism, cell, or virus
Reexamination Certificate
active
10429478
ABSTRACT:
A process is described for the delivery of a therapeutic polynucleotide to limb muscle tissue suffering from or potentially suffering from ischemia. The polynucleotide is inserted into a mammalian limb vessel such as an artery. Delivery efficiency and distribution is enhanced by combining injection of a solution containing the polynucleotide with the use of an externally applied cuff.
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Budker Vladimir G.
Hagstrom James E.
Hegge Julia
Subbotin Vladimir
Wolff Jon A.
Ekena Kirk
Johnson Mark K.
Mirus Bio Corporation
Whiteman Brian
LandOfFree
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