Devices and methods for using centripetal acceleration to drive

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving hydrolase

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435 4, 435 24, 435 32, 4352831, 4352871, 435 25, 435 28, 422 50, 422 681, 422 8201, 422146, C12Q 137

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active

060635894

ABSTRACT:
This invention provides methods and apparatus for performing microanalytic and microsynthetic analyses and procedures. Specifically, the invention provides a microsystem platform for use with a micromanipulation device to manipulate the platform by rotation, thereby utilizing the centripetal force resulting from rotation of the platform to motivate fluid movement through microchannels embedded in the microplatform. The microsystem platforms of the invention are also provided having microfluidics components, resistive heating elements, temperature sensing elements, mixing structures, capillary and sacrificial valves, and methods for using these microsystems platforms for performing biological, enzymatic, immunological and chemical assays. An electronic spindle designed rotor capable of transferring electrical signals to and from the microsystem platforms of the invention is also provided.

REFERENCES:
patent: 5622819 (1997-04-01), Herman
patent: 5821116 (1998-10-01), Herman

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