Devices and methods for preparing pharmaceutical solutions

Details Devices and methods for preparing pharmaceutical solutions Devices and methods for preparing pharmaceutical solutions

1991-03-05

1993-03-23

Millin, V.

Surgery

Container for blood or body treating material, or means used...

Materials mixed within container

604 82, 604 87, 206438, A61B 1900

Patent

active

051960010

ABSTRACT:
A device for the preparation of sterile U.S.P. pharmaceutical solutions for intravenous use includes a transparent first bag, a transparent second bag, and a filtration unit. The filtration unit has an inlet tube and an outlet tube, the inlet tube of the filtration unit being attached to an outlet port in the first bag and the outlet tube being connected to the second bag. The first bag has a resealable inlet port through which aqueous U.S.P. solvent and unit dose holders containing medicaments may be introduced. The unit dose holders which contain ingredients to be mixed with a solvent have air-filled portions separated from ingredient containing portions by a rupturable plastic portion. The contents of the holder may be released by manipulation of the air-filled portions. The unit dose holders are labeled such that the labeling may be read through the transparent bag. The unit dose holders may be inserted in combinations within the first bag combined so that the combination of the unit dose holder ingredients can produce a near neutral pH solution when the medicaments are released into the aqueous U.S.P. solvent. The solutions produced in the first bag may then be filtered into the second bag and administered to a patient.

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Avis et al, "Sterile Preparation for the Hospital Pharmacist", Ann Arbor Science .COPYRGT.1982.
Instructions from Abbott Laboratories on ADD-VANTAGE .RTM. System container for pharmaceuticals.
Photograph of pharmaceutical container by DEY-PAK.TM..

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