Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1997-12-16
2000-12-26
Arthur, Lisa B.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 911, 435 912, C12Q 168, C12P 1934
Patent
active
06165714&
ABSTRACT:
The invention provides devices and methods for use in detecting nucleic acid analytes in samples. The devices each include a solid support to which is bound a two-dimensional distribution or field of nucleic acid probes that each bind to a nucleic acid analyte, which is detected by use of amplification methods.
REFERENCES:
patent: 4786600 (1988-11-01), Kramer et al.
patent: 4988617 (1991-01-01), Landegren et al.
patent: 5112734 (1992-05-01), Kramer et al.
patent: 5376692 (1994-12-01), Park et al.
patent: 5399491 (1995-03-01), Kacian et al.
patent: 5407798 (1995-04-01), Martinelli et al.
patent: 5610287 (1997-03-01), Nikiforov et al.
patent: 5616478 (1997-04-01), Chetverin et al.
patent: 5747244 (1998-05-01), Sheridan et al.
patent: 5759773 (1998-06-01), Tyagi et al.
patent: 5837466 (1998-11-01), Lane et al.
Seelig et al. Tetrahedron Lett. 38(44):7729-7732 (1997).
Chetverin et al., Database WPI Week 9629, Derwent Publications Ltd., London, GB; AN 96-285502; XP002095312 & RU A(2048522), Nov. 20, 1995.
Logsdon et al., Chemical Abstracts, vol. 119, No. 15, Oct. 11, 1993 Columbus, OH; abstract No. 160710 XP002102405.
Nicholson et al., "Accurate in vitro cleavage by RNase III of phosphorothioate-substituted RNA processing signals in bacteriophage T7 early mRNA" Nucleic Acid Research, vol. 16, No. 4, 1988, pp 1577-1591 XP000572714.
Seelig B. et al., "Site-specific modification of enzymatically synthesized RNA: Transcription initiation and Diels-Alder reaction" Tetrahedron Letters, vol. 38, No. 44, 1997, pp 7729-7732, XP004093407.
Burg et al., "Real Time Fluorescence Detection of RNA Amplified by Q.beta. Replicase", Analytical Biochemistry 230:263-272, (1995).
Chu et al., "Derivatization of Unprotected Polynucleotides," Nucleic Acids Research, 11:6513 (1983).
Dolinnaya et al.., "The use of BrCN for assembling modified DNA . . . with water-soluble carbodiimide", Nucleic Acids Research, 19:3067-3071, (1991).
Dolinnaya et al., "Site-directed modification of DNA duplexes by chemical ligation", Nucleic Acids Research, 16:3721-3738, (1988).
Dolinnaya et al., "Oligonucleotide circularization by template-directed chemical ligation", Nucleic Acids Research, 21:5403-5407, (1993).
Moody et al., "Evolution of Host Cell RNA into Efficient Template RNA by . . . in Untemplated Reactions", Biochemistry, 33:13836-13847, (1994).
Persing, "In Vitro Nucleic Acid Amplification Techniques", Diagnostic Molecular Microbiology, pp. 51-77. (1993).
Strobel et al., "Efficient Ligation of a Highly Structured RNA using T4 DNA Ligase", Editorial Comments, 19:89-91 (1992).
Tyagi et al., "Molecular Beacons: Probes that Fluoresce upon Hybridization", Nature Biotechnology, 14:303-308 (1996).
Farrell Michael P.
Lane David J.
Arthur Lisa B.
Galloway Norval B.
Vysis, Inc.
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