Devices and methods for delivering active agents to target...

Surgery – Means for introducing or removing material from body for... – Treating material applied to or removed from external...

Reexamination Certificate

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C424S045000

Reexamination Certificate

active

07959617

ABSTRACT:
The subject invention provides novel, inexpensive, and highly effective methods and devices for convenient and effective wound irrigation. In one embodiment the subject invention provides a discharge means for a reservoir housing containing irrigation solution wherein the discharge means has one or more specifically designed nozzles through which a sufficient volume of the irrigation solution can pass at an appropriate pressure.

REFERENCES:
patent: 2005/0113794 (2005-05-01), Rucinski
patent: 2005/0148958 (2005-07-01), Rucinski
patent: 2005/0191247 (2005-09-01), Drake et al.
patent: 2007/0184114 (2007-08-01), Cevc
patent: WO 02/07799 (2002-01-01), None
patent: WO 2007/070861 (2007-06-01), None
Yu, H.Y.H., et al. “Chlorhexidine for Irrigation of Vas: a Clinical Trial and the Study of Viability of Non-Motile Sperms in Post-Vasectomy Patients with Trypan Blue Uptake,”Bristish Journal of Urology, 1976, pp. 371-375, vol. 48.
Anderson, Maxwell H., “A Review of the Efficacy of Chlorhexidine on Dental Caries and the Caries Infection,”Journal of the California Dental Association, Mar. 2003.
Demling, Robert H. and Waterhouse, Barbara, “The Increasing Problem of Wound Bacterial Burden and Infection in Acute and Chronic Soft-Tissue Wounds Caused by Methicillin-ResistantStaphylococcus aureus,” Journal of Burns and Wounds, Nov. 2007, vol. 7, pp. 86-98.
MacNeill, S. et al., “Effects of tetracycline hydrochloride and chlorhexidine gluconate onCandida albicans: An in vitro study,”Journal of Clinical Periodontology, Jan. 1997, vol. 24, pp. 753-760.
O'Grady, Naomi P. et al., “Guidelines for the Prevention of Intravascular Catheter-Related Infections,”Morbidity and Mortality Weekly Report, Aug. 2002, vol. 51, No. RR10, pp. 1-26.
Puryan, Kenan et al., “Chlorhexidine Gluconate: An Ideal Scolicidal Agent in the Treatment of Intraperitoneal Hydatidosis?”World Journal of Surgery, Feb. 2005, vol. 29, No. 2, pp. 227-230.
Rahman, M. Rezanur et al., “Trial of chlorhexidine gluconate for fungal corneal ulcers,”Ophthalmic Epidemiology, Sep. 1997, vol. 4, No. 3, pp. 141-149.
Regulatory Resources Group, Inc., “Traditional 510(k): IRRIMAX Corporation's IRRISEPT™ Wound Cleansing System,” Mar. 19, 2008, application for FDA approval.
Xuguang, Sun et al., “Pharmacokinetics of Chlorhexidine Gluconate 0.02% in the Rabbit Cornea,”Journal of Ocular Pharmacology and Therapeutics, 2006, vol. 22, No. 4, pp. 227-230.

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