Devices and methods for analyte detection using distorted...

Details Devices and methods for analyte detection using distorted... Devices and methods for analyte detection using distorted...

2006-10-03

2010-06-29

Alexander, Lyle A (Department: 1797)

Chemistry: analytical and immunological testing

Process or composition for determination of physical state...

Of crystal or crystalline material

C436S164000, C436S165000, C436S180000, C436S518000, C436S532000, C422S050000, C422S052000, C422S068100, C422S073000

Reexamination Certificate

active

07745220

ABSTRACT:
The present invention provides devices and methods for detection of analytes based on measuring the anchoring strength of liquid crystals having distorted geometries. Methods for detecting an analyte in a sample include the steps of: (a) capturing an analyte on a substrate surface wherein the substrate surface defines an easy axis when in contact with a liquid crystal. Substrate surface and liquid crystal are brought into contact and an analyte-dependent departure in the orientation of the liquid crystal from the easy axis of the substrate surface is measured. This departure indicates the presence of the analyte in the sample.

REFERENCES:
patent: 6075512 (2000-06-01), Patel et al.
patent: 6284197 (2001-09-01), Abbott
patent: 2002/0055093 (2002-05-01), Abbott
patent: 2004/0185551 (2004-09-01), Niehaus
patent: WO02075294 (2002-09-01), None
V.P. Vorflusev, H.S. Kitzerow, V.G. Chigrinov, “Azimuthal anchoring of liquid crystals at the surface of photo-induced anisotropic films”, 1997, Appl. Phys. A, 64, 615-618.
Tingey, M., et al., Langmuir, vol. 20, No. 16:6818-6826 (2004).
Tingey, M., et al., Advanced Materials, vol. 16, No. 15:1331-1336 (2004).
Gupta, V. K., et al., Science, vol. 279, No. 5359:2077-2080 (1998).

Affiliated with

Also associated with

Rating

Devices and methods for analyte detection using distorted... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Devices and methods for analyte detection using distorted..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Devices and methods for analyte detection using distorted... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4199693