Device having a liquid flowpath

Details Device having a liquid flowpath Device having a liquid flowpath

2006-03-07

2006-03-07

Olsen, Kaj K. (Department: 1753)

Chemistry: electrical and wave energy

Apparatus

Electrophoretic or electro-osmotic apparatus

C422S105000

Reexamination Certificate

active

07008521

ABSTRACT:
A micro-reactor is provided with a mixture of channels having larger cross-sectional areas (17′,22′,25′,27′,31′,33′) and channels having smaller cross-sectional areas (40a′,40b′,40c′). The smaller channels (40a′,40b′,40c′) resist liquid movement driven by hydrostatic force but allow liquid movement driven by electro-osmotic force. Accordingly liquid flow is almost entirely driven by electro-osmotic force. The smaller channels (40a′,40b′,40c′) are formed by etched grooves which are closed by a planar surface13. This allows the cross-sectional areas of the smaller channels to be closely and reproducibly controlled.

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Raymond, et al.; “Continuous Sample Pretreatment Using a Free-Flow Electrophoresis Device Integrated onto a Silicon Chip”; Analytical Chemistry, vol. 66, No. 18, Sep. 15, 1994, pp. 2858-2865.

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