Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1995-04-06
1998-08-25
Chin, Christopher L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
422 55, 422 57, 422 58, 422 61, 435 792, 435 793, 435 794, 4352871, 4352872, 4352884, 4352885, 4352887, 435810, 436514, 436518, 436524, 436527, 436528, 436164, 436172, 436537, 436805, 436807, 436808, 436810, G01N 3353, G01N 33543, G01N 33558
Patent
active
057982155
ABSTRACT:
A device and method for its use in diagnostic assays are provided. The device comprises at least one assay path, where an assay path includes a main flow path and at least one side reagent channel. The main flow path begins at a sample addition port, continues through a main reagent area into an incubation area and ends in a waste area. In fluid communication with the main flow path is at least one side reagent channel that begins at a liquid addition port, continues through a side reagent area and ends in said main channel at a region between the main reagent and waste areas, usually upstream from the incubation area. Agitation means may be included in at least one of the main and side reagent areas and/or the incubation area. At least one fluid interruption means located at various positions along the main and side reagent channels upstream from the incubation area provide for control over reagent interaction and fluid flow through the device. Applications in which the device finds use include diagnostic assays employing signal producing systems based on the interactions of specific binding pair members, where an optical signal is related to the presence of analyte.
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Bloom Nicole D.
Cathey Cheryl A.
Langford Jeffrey B.
Paul David J.
Ribi Hans O.
Biocircuits Corporation
Chin Christopher L.
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