Device for treating vulnerable plaque

Details Device for treating vulnerable plaque Device for treating vulnerable plaque

2005-05-26

2009-06-30

Truong, Kevin T (Department: 3734)

Surgery

Means for introducing or removing material from body for...

Treating material introduced into or removed from body...

C606S192000

Reexamination Certificate

active

07553292

ABSTRACT:
A method of treating vulnerable plaque comprising intentionally damaging or rupturing the vulnerable plaque using a wingless balloon which is inflated from a wingless unexpanded diameter to a limited expanded diameter. This process produces significant increase in ECM synthesis at the site of the damage or rupture. As a result, the method strengthens the vulnerable plaque while minimizing or avoiding damage to the surrounding wall of the body lumen or damaging a stable plaque mistakenly believed to be a vulnerable plaque. The method of the invention is particularly useful in treating a fibroatheroma type of vulnerable plaque. In one embodiment, the balloon is self-limiting such that it expands compliantly at initial inflation pressures, and above nominal pressure it expands noncompliantly. In an alternative embodiment, the balloon is inflated using a diameter-limiting device, such as a device which limits the inflation pressure or the volume of inflation fluid in the balloon.

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