Device for the purification of synthetic oligonucleotides

Details Device for the purification of synthetic oligonucleotides Device for the purification of synthetic oligonucleotides

1993-11-29

1995-05-09

Redding, David A.

Chemical apparatus and process disinfecting, deodorizing, preser

Analyzer, structured indicator, or manipulative laboratory...

Means for analyzing liquid or solid sample

436 94, 210656, 210659, 935 1, 935 86, 935 88, G01N 3002, G01N 3088

Patent

active

054137624

ABSTRACT:
A device for the purification of synthetic oligonucleotides, characterized by comprising means for switching between purification with an affinity column which recognizes trityl groups, in cases where trityl groups are bonded, and purification with a disposable stepwise reverse phase chromatography column in cases where no trityl groups are bonded. The device makes it possible for any person to easily perform high-degree purification, simply by setting the synthesized oligonucleotides. Furthermore, it accomplishes both a method using an affinity column cartridge and a method for purification by HPLC.

REFERENCES:
patent: 4948882 (1990-08-01), Ruth
patent: 5049656 (1991-09-01), Lewis et al.
Gauer, R. K. "High-performance liquid chromatography of synthetic oligonucleotides." J. of Chromatography, 549 (1991) 207-215.
Seliger, H. et al. "Polymer Support Synthesis." J. of Chromatography, 397, (1987) 141-51.

Affiliated with

Also associated with

Rating

Device for the purification of synthetic oligonucleotides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Device for the purification of synthetic oligonucleotides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Device for the purification of synthetic oligonucleotides will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1703605