Device for selective destruction of cells

Details Device for selective destruction of cells Device for selective destruction of cells

1988-03-11

1991-07-30

Coven, Edward M.

Surgery

Instruments

Light application

128396, 604 5, A61M 501

Patent

active

050356933

ABSTRACT:
Apparatus for selective destruction or inactivation of cells is disclosed wherein cells are arrayed in a plane for successive illumination, by optical X-Y scanning devices, with a first low power red light beam to produce in particular cells certain radiations responsive to the illumination. These response radiations are detected and used to enable a second higher powered light beam directed through substantially the same optical scanning paths, to destroy or inactivate the cells producing the response radiations. The illumination, response, detection, and high power radiation steps are accomplished by devices acting in times short as compared to the X-Y scanning devices so as to make the accurate treatment of each of large numbers of cells highly effective. Alternate embodiments disclose the use of a signal laser light source to selectively provide both the low and high powered light beams, various X-Y scanning arrangements, and various devices for correcting the spherical aberration of the scanned beams in variously positioned image planes.

REFERENCES:
patent: 3883683 (1975-05-01), Pardes
patent: 4316467 (1982-02-01), Muckerheide
patent: 4395397 (1983-07-01), Shapiro
patent: 4538613 (1985-04-01), Rosenberg
patent: 4564012 (1986-01-01), Shimada
patent: 4640573 (1987-02-01), Kataoka et al.
patent: 4641650 (1987-02-01), Mok
patent: 4683889 (1987-08-01), Edelson
Bartz et al, "Simultaneous Dual Scanner" 4/71.
Shogren "Scanning System for Copier" 12/81.

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