Chemistry: molecular biology and microbiology – Apparatus – Including condition or time responsive control means
Patent
1995-08-07
1996-09-10
Kepplinger, Esther
Chemistry: molecular biology and microbiology
Apparatus
Including condition or time responsive control means
4352871, 4352877, 4352887, 422 56, 436 46, 436808, 2047775, G01N 2101
Patent
active
055545319
ABSTRACT:
Assays for liquid analytes are performed on a bibulous matrix containing dried reagents which produce a visibly detectable reaction product. Application of liquid sample to the bibulous matrix is detected by measuring a drop in resistance across the matrix. A preferred test article for performing the method includes the matrix and a pair of spaced-apart electrodes in electrical contact with a reaction zone on the matrix. The test article is used in combination with a detection unit having means for probing the electrodes to determine when electrical resistance in the matrix has decreased. The assay methods and apparatus are particularly useful for performing enzyme assays where signal developed as a function of time is critical.
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Avocet Medical, Inc.
Cano Milton I.
Kepplinger Esther
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