Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Chemiluminescent
Patent
1989-10-23
1993-09-14
Housel, James C.
Chemical apparatus and process disinfecting, deodorizing, preser
Analyzer, structured indicator, or manipulative laboratory...
Chemiluminescent
422 56, 422 58, 422 8205, 422101, 436178, 436180, 435291, 435805, G01N 128, G01N 33543
Patent
active
052446301
ABSTRACT:
A disposable device suitable for performing automated solid-phase diagnostic assays which employs microparticles to complex an analyte and where the microparticle complex becomes retained and immobilized on a fibrous matrix such that the presence of analyte on the microparticles can be detached by optical means. A device is disclosed having a plurality of well pairs comprising a sample well for receiving a sample and reagents for forming a reaction mixture, a read well comprising (a) an entrance port and holder for receiving and holding a quantity of sample and assay reagents, (b) a fibrous matrix for retaining and immobilizing microparticle/analyte complexes for detection, said fibrous matrix positioned below said holder, and having an average spatial separation of fibers greater than the average diameter of said microparticles, (c) absorbent material positioned below said fibrous matrix for assisting the flow of sample and assay reagents through said fibrous matrix, (d) walls or ribs for creating a substantially light-tight real surrounding the wells, (e) a vent for venting air entrapped in the absorbent material and which is displaced by fluids absorbed therein, and (f) a passage between the sample well and the read well whereby sample and reaction mixtures can be transferred and washed from said sample well into said read well without being contacted by any apparatus.
REFERENCES:
patent: 3997404 (1976-12-01), Waders
patent: 4246339 (1981-01-01), Cole et al.
patent: 4396579 (1983-08-01), Schroeder et al.
patent: 4923680 (1990-05-01), Nelson
patent: 4999163 (1991-03-01), Lennon et al.
patent: 5006309 (1991-04-01), Khalil et al.
Hanna Charles F.
Huff Denise G.
Khalil Omar S.
Zurek Thomas F.
Abbott Laboratories
Bhat N.
Collins Daniel W.
Housel James C.
Porembski Priscilla E.
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