Device for moving a target-bearing solid through a liquid for de

Details Device for moving a target-bearing solid through a liquid for de Device for moving a target-bearing solid through a liquid for de

1992-06-01

1994-11-15

Scheiner, Toni R.

Chemical apparatus and process disinfecting, deodorizing, preser

Analyzer, structured indicator, or manipulative laboratory...

Calorimeter

422 99, 422101, 422102, 435 6, 435 75, 435 79, 435 792, 435 794, 435810, 436165, 436518, 436528, 436531, 436532, 436533, 436534, 436538, 436807, 436809, 436810, 530333, 530334, 530338, G01N 33537, G01N 33546

Patent

active

053645910

ABSTRACT:
There are described a device and method for doing confined reactions such as PCR amplification and detection, wherein solids (e.g., beads) used to obtain separation between bound and "free" label reagents, are transferred from region to region, specifically through a wash liquid so as to wash off the "free" label reagent from the solids. Separate chambers have dividers that are overcome by piercing or by liquification, to create passageways for the transfer of the solids. The passageways remain contained within the device.

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J. Findlay et al., "Automated Closed-Vessel System for in Vitro Diagnostics Based on Polymerase Chain Reaction," in Clin. Chem. vol. 59, No. 9 (1993) pp. 1927-1933.
F. Braun, "Brave New World Described at San Diego Conference," Clinical Chemistry News, vol. 19, No. 1, Jan. 1993 pp. 1, 2, 10.

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