Device for local drug delivery and methods for using the same

Details Device for local drug delivery and methods for using the same Device for local drug delivery and methods for using the same

1993-04-14

1995-03-21

Kishore, G. S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

623 1, 623 12, A61F 204, A61F 206

Patent

active

053993527

ABSTRACT:
A device for the local delivery of a substance into a natural tissue conduit in the mammalian body, having a first clement capable of contacting the lumen of the conduit and a second element which overlays first element, a reservoir being formed between the first element and the second element, the interior of the reservoir being capable of fluid communication with the conduit such that a substance placed in the reservoir is delivered into the conduit. Also provided are methods of locally delivering a substance into a natural tissue conduit in the mammalian body utilizing the device of the present invention.

REFERENCES:
patent: 3797485 (1974-03-01), Urquhart
patent: 4687482 (1987-08-01), Hanson
patent: 5192310 (1993-03-01), Henveck et al.
Hanson et al., Arteriosclerosis 5:595-603 (1985).
Kelly et al., Blood 77:1006-1012 (1991).
Hanson et al., Proc. Natl. Acad. Sci. USA 85:3184-3188 (1988).

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