Device for local drug delivery and methods for using the same

Details Device for local drug delivery and methods for using the same Device for local drug delivery and methods for using the same

1994-01-28

1996-06-04

Azpuru, Carlos

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

604 96, 604101, 604264, 604280, 604281, A61M 25088

Patent

active

055230920

ABSTRACT:
A device for the local delivery of a substance into a natural tissue conduit in the mammalian body. The device has a substance delivery segment which provides a means for locally delivering a substance into the boundary layer of fluid flowing through the conduit without disrupting the fluid flow therethrough. For example, an indwelling catheter is provided for endovascular delivery of a substance locally to a targeted treatment area. Also provided are methods of locally delivering a substance into a natural tissue conduit in the mammalian body utilizing the device of the present invention.

REFERENCES:
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patent: 4994033 (1991-02-01), Shockey et al.
patent: 5049132 (1991-09-01), Shaffer et al.
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Muller et al., "Intramural Methotrexate Therapy for the Prevention of Neointimal Thickening After Balloon Angioplasty," JAAC 20(2):460-466 (Aug., 1992).
"The Bullett: Site-Specific Drug Delivery MicroCatheter," Promotional material by CardioVascular Dynamics, Inc., Pleasanton, CA (1993).
"Dispatch: You Can See the Dispatch Difference," Promotional material by SCIMED Life Systems, Inc., Maple Grove, MN, on the Dispatch Coronary Infusion Catheter (1994).

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