Device for isolating a component of a physiological sample

Chemistry: analytical and immunological testing – Automated chemical analysis – Utilizing a centrifuge or compartmented rotor

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436 49, 436174, 436177, 436180, 422 63, 422 72, 422100, 422101, 422103, 435 4, 435 6, G01N 3510

Patent

active

059358580

ABSTRACT:
Devices and methods are provided for the isolation of one or more components of a sample. The self contained device of the subject invention includes a reaction chamber, at least one reagent chamber containing a sealed, predetermined amount of reagent, at least one waste chamber, an entry port and a medranism for moving the reaction chamber sequentially into fluid communication with each of these other components. Also provided are methods of using the subject devices to perform procedures in which an initial sample is sequentially subjected to one or more reagent addition and washing steps. The subject devices and methodology are particularly suited to the isolation of nucleic acids from physiological samples.

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