Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing
Reexamination Certificate
2011-04-19
2011-04-19
Bowers, Nathan A (Department: 1775)
Chemistry: molecular biology and microbiology
Apparatus
Including measuring or testing
C435S288300, C435S287900, C435S288500, C435S287800, C435S305100, C435S305200, C435S305300, C435S287100, C435S297500, C435S287300, C422S091000
Reexamination Certificate
active
07927867
ABSTRACT:
The current invention is directed towards a device that useful for studying cell migration. It is preferred that the device is configured to study stem cell, particularly hematopoetic stem/precursor cell homing. The device allows for detailed analysis of the various phases of the multiphase homing process. There are also provided herein, novel methods of using the device, including, but not limited to, dissection of the homing process under microenvironmental conditions mimicking healthy conditions, diseased conditions, inflammatory conditions, drug treatment conditions and experimental conditions.
REFERENCES:
patent: 5190878 (1993-03-01), Wilhelm
patent: 5460945 (1995-10-01), Springer et al.
patent: 5599688 (1997-02-01), Grass
patent: 6119506 (2000-09-01), Gibson et al.
patent: 6706520 (2004-03-01), Han et al.
patent: 2003/0215941 (2003-11-01), Campbell et al.
patent: 2004/0132175 (2004-07-01), Vetillard et al.
patent: 2007/0272000 (2007-11-01), Kahl et al.
patent: 0112155 (1984-06-01), None
Siminovitch, L., et al.,“The Distribution of Colony-forming Cells Among Spleen Colonies,” J Cell Comp Physiol, 1963, 327-336, 62.
Lord, B.I., et al., “On the Late Seeding of CFU-S to the Spleen: 8 vs 12-day CFU-S,” Exp. Hematol., 1989, 836-842, 17.
Visser, J.W.M., et al., “In vivo studies on the regeneration kinetics of enriched populations of . . . ,” Cell Tissue Kinet., 1983, 385-392, 16.
Chiu, Jeng-Jiann, et al., “Shear stress inhibits adhesion molecule expression in vascular . . . ,” Blood, 2003, 2667-2674, 101(7).
Nerem, Robert M., “Shear force and its effect on cell structure and function,” ASGSB Bulletin, 1991, 87-94, 4(2).
Barakat, Abdul I., “Responsiveness of vascular endothelium to shear stress . . . ,” International Journal of Molecular Medicine, 1999, 323-332, 4.
Shyy, John Y-J., “Mechanotransduction in endothelial responses to shear stress . . . ,” Biorheology, 2001, 109-117, 38.
Fisher, Aron B., “Endothelial cellular response to altered shear stress,” Am J Physiol Lung Cell Mol Physiol, 2001, L529-L533, 281.
Vermeulen, et al., (1998) Blood, 92(3):894-900.
Hendrikx PJ, et al., (1996) Exp Hemat 24:129-140.
Oostendorp, et al., (2000) Bone Marrow Transpl., 26(5):559-566.
Mazo, et al., (1998) J Exp Med 188(3):465-474.
Cinamon, et al., (2001) J Leukoc Biol 69:860-866.
Bautz, et al., (2000) Exp Hematol 28(6):700-706.
Hardy, Minguell, (1993) Scanning Microscopy 7(1):333-341.
Hardy, Megason, (1996) Hematol Oncol 14:17-27.
Wright, et al., (2001) Science 294:1933-1936.
Topper, et al., (1999) Mol Med Today 5(1):40-46.
Nerem, et al., (1998) Am J Med Sci 16(3):169-175.
Ballermann, et al., (1998) Kidney Int Suppl 67:S100-108.
Rainger, et al., (2001) Immunol Methods 255(1-2):73-82.
Bowers Nathan A
Cascade Life Sciences, Inc.
Kohn David M.
Lewis Kohn & Fitzwilliam LLP
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