Device for evaluating in vitro cell migration under flow...

Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing

Reexamination Certificate

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C435S288300, C435S287900, C435S288500, C435S287800, C435S305100, C435S305200, C435S305300, C435S287100, C435S297500, C435S287300, C422S091000

Reexamination Certificate

active

07927867

ABSTRACT:
The current invention is directed towards a device that useful for studying cell migration. It is preferred that the device is configured to study stem cell, particularly hematopoetic stem/precursor cell homing. The device allows for detailed analysis of the various phases of the multiphase homing process. There are also provided herein, novel methods of using the device, including, but not limited to, dissection of the homing process under microenvironmental conditions mimicking healthy conditions, diseased conditions, inflammatory conditions, drug treatment conditions and experimental conditions.

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