Chemistry: molecular biology and microbiology – Apparatus
Reexamination Certificate
2007-05-08
2007-05-08
Forman, B J (Department: 1634)
Chemistry: molecular biology and microbiology
Apparatus
C435S287200, C422S068100, C422S082010, C530S300000, C530S350000
Reexamination Certificate
active
10335043
ABSTRACT:
An analysis device includes an electrode arrangement, a current/voltage provider, and a circuit analyzer. The electrode arrangement has an interdigitated electrode pair including a first electrode and a second electrode. Coupled to the electrode arrangement is a signal generator adapted to provide a signal (e.g., an alternating current or voltage) having a selected range of frequencies. The analyzer is coupled to the electrode arrangement and is operative to analyze an electrical parameter of the circuit as the signal is applied. An analytic method includes measuring changes in one or more parameters of the circuit over the range of frequencies. By such measurement, the device can determine whether a target moiety has been bound by a probe attached to the electrode(s). The device can also specifically identify the intermolecular system detected, i.e., by “finger-printing” the electrical response of each molecule or intermolecular complex.
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Solanki Rajendra
Vandenbark Arthur A.
Forman B J
Marger & Johnson & McCollom, P.C.
Oregon Health & Sciences University
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