Device for determining the concentration of at least one substan

Details Device for determining the concentration of at least one substan Device for determining the concentration of at least one substan

1991-07-18

1993-09-14

Cohen, Lee S.

Surgery

Truss

Pad

128DIG12, 604153, A61B 500

Patent

active

052439828

ABSTRACT:
A device for determining the concentration of at least one substance in organic tissue includes a subcutaneous needle for insertion into the tissue and a pumping and suction unit which is controlled by a microprocessor and is used for delivering a perfusion fluid and draining it after its partial equilibration with the tissue. The device further includes a sensing unit connected to the microprocessor for determining the concentration of the substance to be analyzed and one or more marker variables. The perfusion fluid, a calibrating solution and at least one drug are provided in replaceable metering ampoules sealed with membranes, whose metering plungers can be actuated by a drive unit controlled by the microprocessor. The metering ampoules communicate with a master capillary leading from the pumping and suction unit to the subcutaneous needle; communication is established via capillary tubes piercing the membranes.

REFERENCES:
patent: 3405706 (1968-10-01), Cinqualbre
patent: 4676256 (1987-06-01), Golden
patent: 4689042 (1987-08-01), Sarnoff et al.
patent: 4784157 (1988-11-01), Halls et al.
patent: 4795441 (1989-01-01), Bhatt
patent: 4846797 (1989-07-01), Howson et al.
patent: 4850972 (1989-07-01), Schulman et al.
patent: 4957490 (1990-09-01), Byrne et al.
patent: 5097834 (1992-03-01), Skrabal
International Publication No. WO88/05643, published 11 Aug. 1988, to Falko Skrabal.

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